The Drug Explorer

Search the nephrotoxic landscape

A live index of 240+ anti-cancer agents, cross-filterable by injury signature, drug class, nephron segment, severity, and era. Profiled agents open to a full citation-grounded page; the rest are catalog entries with their signature kidney signal.

7 agents · filtered from 240

Azacitidine

Vidaza · Hypomethylating agent

Profile

Renal tubular acidosis and rare AKI.

ATNFANCLYTE
ModerateOpen →

Ifosfamide

Ifex · Oxazaphosphorine alkylator

Profile

Chloroacetaldehyde → Fanconi syndrome.

FANCATNLYTE
SevereOpen →

Imatinib

Gleevec · BCR-ABL TKI

Profile

Fluid retention; rare Fanconi and AKI.

LYTEFANCATN
MildOpen →

Lenalidomide

Revlimid · Immunomodulatory drug (IMiD)

Profile

Renally cleared; AKI and rare Fanconi/TMA.

ATNFANCTMA
ModerateOpen →

Nirogacestat

Ogsiveo · Gamma-secretase inhibitor

Profile

2023 desmoid-tumor agent; phosphate/electrolyte disturbance.

LYTEFANC
MildOpen →

Streptozocin

Zanosar · Nitrosourea alkylator

Profile

Classic proximal tubular toxin → Fanconi and dose-limiting AKI.

FANCATNLYTE
SevereOpen →

Trastuzumab deruxtecan

Enhertu · Antibody-drug conjugate (HER2/DXd)

Profile

Emerging AKI/proteinuria reports — under-published.

ATNFANCLYTE
ModerateOpen →